血液透析患者的萨科白症:患病率,独立风险因素和功能影响 - - 一项多中心跨部门研究
Rym Ben Othman1,2,3, Amani Balti2, Sabrine Boukhris2
1Department A, Institut National Zouhair Kallel de Nutrition et de Technologie Alimentaire, 11 rue Jbel Lakhdar, Bab Saadoun, Tunis 1007, Tunisia.
Journal of clinical medicine
|October 16, 2025
概括
麻症影响42.4%的血液透析患者,与糖尿病和更长时间的治疗有关. 这种情况严重影响身体功能和生活质量,需要早期查和干预.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 营养科学 营养科学
背景情况:
- 萨科佩尼亚是血液透析患者常见的并发症,显著恶化临床结果,发病率和生活质量.
- 有限的数据存在于sarcopenia的患病率,风险因素和影响,特别是在发展中国家.
研究的目的:
- 为了确定突尼斯血液透析患者中肉类的患病率.
- 在这个人群中确定与肉类相关的独立风险因素.
- 评估萨科佩尼亚对身体表现,营养状况和生活质量的影响.
主要方法:
- 一项多中心的横截面研究,涉及118名血液透析患者.
- 基于EWGSOP2标准,评估肌肉强度,质量和身体表现 (例如,手握强度,步行速度,SPPB,TUG) 的萨尔科佩尼亚诊断.
- 还评估了营养摄入量,生活质量 (SF-36) 和功能状态 (巴特尔指数).
主要成果:
- 麻症的患病率为42.4%,受影响个体的身体表现 (力量,步行速度,SPPB,TUG) 显著降低.
- 麻症患者表现出下肢周长,生活质量降低 (SF-36),功能独立性降低 (巴特尔指数).
- 萨科佩尼亚的独立预测因素包括糖尿病 (OR=2.14) 和更长的血液透析持续时间 (OR=1.56). 较低的SPPB得分与肉症相关 (OR=0.48).
结论:
- 萨科佩尼亚在血液透析患者中非常普遍,并且独立地与糖尿病,治疗时间和体力表现下降有关.
- 萨科佩尼亚严重影响生活质量和日常活动的表现.
- 使用功能测试进行例行查,加上早期干预,如身体康复,营养支持和血糖控制,至关重要.
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