在阻塞性睡眠呼吸暂停中,抑郁症状与心率变化的相关性
Ji Hye Shin1, Min Ji Song1, Ji Hyun Kim1
1Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul 08308, Republic of Korea.
Journal of clinical medicine
|October 16, 2025
概括
阻塞性睡眠呼吸暂停 (OSA) 患者的抑郁症状与心率变化 (HRV) 的降低有关,这表明自主功能障碍. 解决抑郁症可能会改善OSA的心血管健康.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 与心血管问题和常见的抑郁症状有关.
- 睡眠障碍和抑郁症都涉及自主功能障碍,但抑郁症在睡眠障碍自主影响中的作用尚不清楚.
研究的目的:
- 在患有OSA的患者中,通过心率变化 (HRV) 测量抑郁症状严重程度和自主功能之间的关联.
主要方法:
- 对1713名患有OSA的成年人的回顾性分析.
- 心率变化 (HRV) 源自在多睡眠时的心电图.
- 使用贝克抑郁 inventory-II (BDI-II) 评估的抑郁症状;通过回归分析的关联.
主要成果:
- 在单变量分析中,较高的BDI-II得分与较低的HRV指数相关 (ln LF, ln HF, ln VLF, ln TP).
- 在多变量分析中,高的BDI-II分数独立地与较低的ln LF,ln HF和ln TP有关,在调整了混因素后.
结论:
- 增加的抑郁症状负担独立地与OSA患者的HRV降低有关.
- 研究结果表明,副交感活动减弱和自主失调.
- 支持OSA综合管理,解决心理和生理方面的问题,以减轻心血管风险.
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