热应激和贝他因会影响猪脂肪组织的脂解
Zaira Pardo1, Manuel Lachica2, Rosa Nieto2
1Animal Nutrition Program, Institute of Agrifood Research and Technology (IRTA), 43120 Constantí, Spain.
Animals : an open access journal from MDPI
|October 16, 2025
概括
热应激减少了猪的脂肪分解,但补充贝他因可以增加脂解. 贝他因可以抵消热应激诱导的脂肪沉积,提供一种策略来管理猪的尸体组成.
科学领域:
- 动物科学动物科学
- 营养生物化学 营养生物化学
- 代谢生理学 代谢生理学
背景情况:
- 热应激 (HS) 挑战了猪生产,可能通过不太了解的机制增加脂肪沉积.
- 比他因是一种代谢修饰剂,可降低猪的尸体脂肪,但其在热应激下对脂解的影响尚不清楚.
研究的目的:
- 在热中性 (TN) 和热应激 (HS) 条件下研究贝他因对伊比利亚猪脂肪组织脂解的影响.
- 为了确定贝他因是否可以抵消HS引起的脂肪代谢变化.
主要方法:
- 来自伊比利亚猪的背部皮下脂肪组织的探头是在TN (37°C) 或HS (41.5°C) 条件下培养的.
- 治疗包括对照剂,贝他因添加剂 (200μM),异二醇 (β-agonist) 和胰岛素.
- 脂解是通过测量糖醇释放到培养基来评估的.
主要成果:
- HS降低了基底脂解,但增加了异二醇刺激的脂解.
- 在TN和HS条件下,贝他因增加了非刺激性脂解.
- 胰岛素在TN和HS条件下减少脂解,在HS条件下更明显的效果.
结论:
- 热应激降低了伊比利亚猪的基础脂解,导致脂肪组织增加.
- 贝他因部分增加脂解,抵消热应激的一些影响.
- 补充贝他因可能是一个可行的策略,以减轻猪的HS诱导肥胖.
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