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在泛美性群体中反复基因组选择的效率

José Marcelo Soriano Viana¹, Jean Paulo Aparecido da Silva¹, Paulo Sávio Lopes²

¹Department of General Biology, Federal University of Viçosa, Viçosa 36570-900, MG, Brazil.

Animals : an open access journal from MDPI

|October 16, 2025

概括

经常性基因组选择增加了 brojler 的遗传收益,其有效性与链接不平衡水平有关. 模型更新和足够的培训数据是最佳基因组选择效率的关键.

科学领域:

动物育种与遗传学
量化遗传学量化遗传学
基因组选择基因组选择

背景情况:

模拟研究提供了具有成本效益的育种者决策支持.
循环基因组选择 (RGS) 是一种强大的基因改进工具.
了解不同遗传模型下的RGS效率至关重要.

研究的目的:

评估泛菌种群中经常性基因组选择的效率.
为了比较RGS在添加物主导和添加物主导下与表现模型的性能.
评估链接不平衡 (LD) 水平对RGS疗效的影响.

主要方法:

模拟了两个肉种群,具有不同的LD水平.
利用了38500个SNP和1000个用于料转换率的基因.
在七个周期中应用了反复的基因组选择.

主要成果:

RGS疗效与LD和基因型变异正相关.
模型更新提高了RGS的有效性;训练集大小为10%/代产生了接近最大的有效性.
附加预测准确度和遗传收益高度相关;近亲繁殖仍然很低.
表皮病,尤其是主导表皮病,显著降低了RGS的疗效.

结论:

在肉中,RGS是有效的,受LD和遗传结构的影响.
低成本的RGS策略可以在最小的培训数据下实现.
表观效应需要在基因组选择模型中仔细考虑,以准确地预测遗传收益.

关键词:

史诗主义就是一种史诗主义.基因组预测基因组预测亲生繁殖是一种繁殖方式.预测的准确性预测的准确性实现了遗传收益的实现.

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Frequency-dependent Selection

Frequency-dependent Selection

When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.