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Updated: Jul 8, 2026

A Liquid Phase Affinity Capture Assay Using Magnetic Beads to Study Protein-Protein Interaction: The Poliovirus-Nanobody Example
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基于IIS的新型图书馆组装技术,用于开发针对IPNv VP2蛋白的纳米体

Camila Pino-Belmar1, Johanna Himelreichs2, Camila Deride2

  • 1Institute of Biochemistry and Microbiology, Faculty of Sciences, Universidad Austral de Chile, Valdivia 5110566, Chile.

International journal of molecular sciences
|October 16, 2025
PubMed
概括

研究人员开发了一种新的纳米体发现管道,以快速生成各种抗体库. 这种方法成功地识别了针对感染性胰腺亡病毒 (IPNv) VP2蛋白的纳米体,有助于水产养殖疾病管理.

关键词:
IPNvv IPNv IPNv IPNv IPNv IPNv IPNv IPNv IPNv IPNv IPNv基于IIS型的组装方法在VP2中,VP2是VP2.单一域抗体 单一域抗体

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Inhibitors of Virion Maturation and Assembly01:19

Inhibitors of Virion Maturation and Assembly

As part of their replication cycle, certain viruses synthesize long precursor proteins called polyproteins within infected host cells. In human immunodeficiency virus (HIV), two major polyproteins are produced: Gag and Gag-Pol. The Gag polyprotein supplies the structural components of the virus, while Gag-Pol includes essential viral enzymes such as reverse transcriptase, integrase, and protease. After synthesis, these polyproteins move to the host cell membrane, where they assemble into an...