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Updated: Jan 15, 2026

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与衰老相关的CCN3表达在CD44阳性干细胞中对于骨关节炎进展的关键要求

Janvier Habumugisha1,2, Ryuichiro Okuda1,3, Kazuki Hirose1,3

  • 1Department of Biochemistry and Molecular Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 5-1 Shikata-cho, 2-chome, Kita-ku, Okayama 700-8525, Japan.

International journal of molecular sciences
|October 16, 2025
PubMed
概括

细胞通信网络因子3 (CCN3) 通过增加软骨分解和限制原生细胞增殖,促进骨关节炎 (OA). 在小鼠中淘汰CCN3减少了OA的发展,这表明CCN3是OA的潜在治疗标.

关键词:
这是一个关节的关节.软骨 软骨 软骨是一种介质细胞干细胞介质细胞干细胞母细胞瘤过度表达的蛋白质骨关节炎是一种关节炎.

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