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辅酶Q10通过减少氧化应激减轻iPSC衍生神经元的化疗诱导的神经毒性

Nidaa A Ababneh1, Razan AlDiqs2, Mohammad H Gharandouq1

  • 1Cell Therapy Center, The University of Jordan, Amman 11942, Jordan.

International journal of molecular sciences
|October 16, 2025
PubMed
概括

辅酶Q10 (CoQ10) 通过保持干细胞衍生神经元中的细胞活力和线粒体功能来保护抗化疗诱导的神经毒性 (CIN). 这种抗氧化剂在癌症治疗期间减轻神经损伤方面表现有前途.

关键词:
辅酶Q10 (CoQ10) 是一种化疗诱导的神经毒性 (CIN)人类诱导的多能干细胞 (hiPSCs)神经保护神经保护反应性氧物种 (ROS) 是一种反应性氧物种.

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