立陶宛吸入剂过敏原敏感性的性别和年龄相关趋势:一项横截面研究
Gabija Didžiokaitė1,2, Aida Kuznecovaitė1, Gabija Biliūtė1
1Faculty of Medicine, Vilnius University, 03101 Vilnius, Lithuania.
International journal of molecular sciences
|October 16, 2025
概括
吸入过敏原敏感性很常见,男性和儿童的发病率更高. 立陶宛人口的不同年龄和性别模式凸显了在过敏诊断中需要人口统计数据的需求.
科学领域:
- 过敏学和免疫学 过敏学和免疫学
- 流行病学 流行病学
- 分子诊断学 分子诊断
背景情况:
- 过敏性疾病受到吸入过敏原的敏感性显著影响.
- 有限的研究存在于特定人群的年龄和性别特定的敏感化模式.
- 了解人口统计学变化对于有效的过敏管理至关重要.
研究的目的:
- 调查在立陶宛的人口群体中吸入过敏原敏感化的流行和分布.
- 用分子诊断分析特定年龄和性别的敏感化模式.
- 确定主导的过敏原组及其与人口因素的关联.
主要方法:
- 通过ALEX2宏阵列 (2020-2022) 测试的658名患者的分子过敏特征的回顾性分析.
- 对吸入过敏原成分的敏感性评估. 吸入过敏原成分.
- 在三个年龄组 (<18,18-44,>44岁) 和按性别的敏感化率的比较.
主要成果:
- 对至少一种吸入过敏原的总体敏感度为62.16%.
- 男性的敏感度明显高于女性,特别是在生殖年龄组 (p=0.0167).
- 儿童患病率最高,随着年龄的增长而下降;树花粉,物皮毛,草花粉和灰尘虫占主导地位. 男孩的敏感度高于男性,女孩的敏感度高于女性.
结论:
- 在立陶宛人群中,在吸入过敏原敏感化模式中发现了明显的与年龄和性别相关的差异.
- 人口因素在过敏诊断中很重要.
- 特定区域的敏感化数据对于为临床护理和公共卫生战略提供信息至关重要.
关键词:
亚历克斯2宏阵列 ALEX2宏阵列与年龄相关的趋势过敏原敏感化过敏原敏感化流行病学流行病学吸入的过敏原是可以吸入的.分子过敏的诊断方法分子过敏的诊断方法呼吸道过敏是一种呼吸道过敏.性别差异的性别差异.更多相关视频
08:44Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
Published on: May 30, 2020
6.5K
05:31Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
10.8K
相关概念视频
Asthma-I: Introduction
3.4K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.4K
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
224
As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
224
