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Updated: Jan 15, 2026

Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue
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Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue

Published on: February 24, 2023

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突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3 突性CXCL3

Yiwei Wu1,2, Jinming Yang1,2, Mengke Chen1

  • 1Department of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200001, China.

International journal of molecular sciences
|October 16, 2025
PubMed
概括

这项研究确定了一种特定的巨细胞子集 (CXCL3+FOSL2+) 驱动类风湿性关节炎 (RA) 关节炎. 在这些巨细胞中准FOSL2/AP-1通路为RA提供了潜在的新治疗策略.

关键词:
AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1 AP-1这就是FOSL2的原因.巨细胞是一个巨细胞.类风湿性关节炎 类风湿性关节炎一个单细胞转录组的转录组.

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