减少每日蛋白质摄入量与艾滋病毒感染者肥胖症之间的关联:一种新的查工具
Carla Greco1, Leila Itani2, Jovana Milic3
1Endocrinology Unit, Department of Medical Specialties, Azienda Ospedaliero-Universitaria di Modena, 41126 Modena, Italy.
Nutrients
|October 16, 2025
概括
艾滋病毒感染者 (MLWH) 和肥胖症患者 (SO) 的蛋白质摄入量较低. 每天摄入0.98g/kg/day的蛋白质可以有效地选MLWH中的SO.
科学领域:
- 营养科学 营养科学
- 艾滋病毒 医学 艾滋病毒 医学
- 老年学是一门学科.
背景情况:
- 肥胖症 (SO) 的特点是身体脂肪增加和肌肉质量/力量减少.
- SO在艾滋病毒感染者 (MLWH) 中很常见,但与饮食的联系尚不清楚.
- 了解饮食在SO中的作用对于这个人群至关重要.
研究的目的:
- 调查MLWH中宏观营养素摄入量和SO之间的关联.
- 评估一个简单的营养标志物,用于在MLWH中选SO.
主要方法:
- 216名MLWH接受了身体组成 (DXA),手握强度和24小时的饮食回忆.
- 参与者被分为SO,非SO和非sarcopenic的非肥胖群体.
- 使用后勤回归和ROC曲线分析来评估营养关联和选准确性.
主要成果:
- 有SO的MLWH年龄较大,BMI较高,但热量和蛋白质摄入量较低.
- 调整后勤回归将较低的蛋白质摄入量 (g/kg/day) 和年龄较大与SO.相关联.
- 蛋白质摄入量为0.98g/kg/天被确定为SO的查切线 (AUC=0.8149,敏感度=71%,特异性=70%).
结论:
- 一种新的每日蛋白质摄入量切断值 (0.98 g/kg/day) 可以选MLWH中的SO.
- 这种标志物可以很容易地在临床环境中实施,用于早期检测SO.
- 对MLWH中SO的饮食干预措施的进一步研究是有必要的.
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