孕妇中维生素D和皮质醇度之间的关联
Kenneth S Addae1, Isaac Agbemafle1, Guangyu Zhu2
1Department of Nutrition, College of Health Sciences, University of Rhode Island, Fogarty Hall 41 Lower College Road, Room 125, Kingston, RI 02881, USA.
Nutrients
|October 16, 2025
概括
这项研究发现,怀孕期间维生素D水平和皮质醇之间没有显著的联系,尽管怀孕妇女中维生素D缺乏的患病率很高. 建议进行进一步的研究.
科学领域:
- 产科和妇科 产科和妇科
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 怀孕期间的维生素D缺乏和高皮质醇与早产等不良结果有关.
- 在孕妇中维生素D和皮质醇之间的相互作用存在有限的研究.
- 这项研究调查了孕妇维生素D和皮质醇度之间的关联.
研究的目的:
- 为了确定维生素D状况与孕妇皮质醇度之间的关联.
主要方法:
- 试点横截面研究 (产前健康和营养研究) 涉及30名健康的孕妇.
- 收集的社会人口统计数据,物质使用,压力,粮食不安全和饮食信息.
- 使用ELISA测量血清25 (((OH) D以检测维生素D状态,10个唾液样本以检测皮质醇.
- 使用线性和逻辑回归模型分析了关联.
主要成果:
- 平均血清25(OH) D为24±9 ng/mL,其中40%的VDD和43%的不足.
- 在调整的线性回归模型 (p=0.57) 中,维生素D状态和皮质醇参数 (AUCg) 之间没有发现显著的关联.
- 后勤回归也显示,维生素D和皮质醇度之间没有显著的关联.
结论:
- 在这个队列中,没有观察到维生素D和皮质醇度之间的显著关联.
- 维生素D缺乏和不足的高患病率凸显了查的必要性.
- 倡导对孕妇进行维生素D查和补充;建议进行前性研究.
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