精准营养和肠脑轴调节在预防神经退行性疾病中的作用
Dilyar Tuigunov1, Yuriy Sinyavskiy1, Talgat Nurgozhin1,2
1Laboratory of Food Biotechnology and Specialty Food Products, Kazakh Academy of Nutrition, Almaty 050008, Kazakhstan.
Nutrients
|October 16, 2025
概括
针对肠-大脑轴的饮食干预措施对神经退行性疾病有希望. 通过精准营养调节肠道微生物群,可以预防和减轻阿尔茨海默氏症和帕金森病等疾病.
科学领域:
- 神经科学是一个神经科学.
- 微生物学 微生物学
- 营养科学 营养科学
背景情况:
- 全球人口老龄化增加了神经退行性疾病 (如阿尔茨海默氏症,帕金森病) 的患病率.
- 肠-大脑轴是新型治疗策略的关键目标.
- 肠道微生物群失调与神经炎症和疾病进展有关.
研究的目的:
- 审查针对神经退行性疾病的肠-大脑轴的精准营养策略.
- 阐明肠道微生物群影响神经退行的机制.
- 总结有关阿尔茨海默病,帕金森病和多发性硬化症的饮食干预的证据.
主要方法:
- 对有关肠道微生物群,精准营养和神经退行症的当前文献进行系统审查.
- 分析由肠道微生物群调节的神经幽默,免疫和代谢途径.
- 检查生物活性成分 (益生菌,益生菌,欧米茄-3,多) 和它们的作用.
主要成果:
- 肠道微生物群失调有助于破坏屏障完整性,神经炎症和蛋白质聚合.
- 特定的饮食成分 (纤维,益生菌,益生菌,omega-3s,多) 调节肠-大脑轴.
- 有证据表明,肠道微生物群与阿尔茨海默氏症,帕金森症和多发性硬化症的病原发生有关.
结论:
- 通过精准营养准肠道微生物群,为预防和缓解神经退行性疾病提供了一个有希望的方法.
- 整合营养基因组学,时间营养学和元基因组学可以个性化饮食策略.
- 调节肠-大脑轴对于在老年人群中保持认知健康至关重要.
关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.帕金森病是帕金森氏症的一种疾病.时间营养 时间营养这种疾病叫做dysbiosis.肠大脑轴 肠大脑轴神经退行性疾病的神经退行性疾病营养基因组学精准营养 精准营养 精准营养更多相关视频
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