来自Gardunha山的野生植物的生物活性潜力:植物化学表征和生物活动
Alexandra Coimbra1, Eugenia Gallardo1,2,3, Ângelo Luís1
1RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Molecules (Basel, Switzerland)
|October 16, 2025
概括
来自七种野生葡萄牙植物的乙醇提取物被分析了其生物活性特性. 鱼 (Cistus salviifolius) 显示出强烈的抗氧化活性,而鱼 (Helichrysum stoechas) 则表现出显著的抗菌作用.
科学领域:
- 民族植物学和植物化学.
- 药理学和自然产品的研究.
背景情况:
- 民间医学利用了许多具有潜在生物活性特性的植物.
- 科学研究对于验证传统用途和发现新型化合物至关重要.
研究的目的:
- 为了评估来自葡萄牙加德纳山 (Gardunha Mountain) 七种野生植物的乙醇提取物的生物活性.
- 识别植物化学成分并评估抗氧化,抗炎,抗微生物和生物相容性.
主要方法:
- 使用UHPLC-timsTOF-MS和光谱测量的植物化学分析.
- 在体外测试抗氧化剂 (根基清除),抗炎和抗微生物 (最小抑制度) 活动.
- 细胞毒性评估以确定生物相容性.
主要成果:
- 提取物含有丰富的黄和酸 (例如,酸,奎尔丁糖化物).
- 在Cistus salviifolius提取物中显示出强大的抗氧化活性 (AAI = 2.84-2.93).
- 赫利克瑞斯 (Helichrysum stoechas) 提取物显示出针对格拉姆阳性细菌和酵母的显著抗菌活性 (MIC = 0.008-0.5 mg/mL).
- Coincya monensis,Rubia peregrina和Umbilicus rupestris的提取物表现出较低的细胞毒性.
结论:
- (Cistus salviifolius) 和 (Helichrysum stoechas) 是生物活性化合物的有希望的来源.
- 这些植物显示出作为天然抗微生物和抗氧化剂的潜力.
- 传统的药用植物为药理学研究提供了宝贵的线索.
更多相关视频
06:47Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
Published on: December 5, 2020
7.2K
11:44Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
Published on: January 19, 2022
2.9K
相关概念视频
01:24Biodiversity and Human Values
Human civilization relies on biodiversity in many ways. Sudden changes in species biodiversity result in environmental changes that can modify weather patterns and therefore human civilizations.
02:40Epiphytes, Parasites, and Carnivores
Plants often form mutualistic relationships with soil-dwelling fungi or bacteria to enhance their roots’ nutrient uptake ability. Root-colonizing fungi (e.g., mycorrhizae) increase a plant’s root surface area, which promotes nutrient absorption. While root-colonizing, nitrogen-fixing bacteria (e.g., rhizobia) convert atmospheric nitrogen (N2) into ammonia (NH3), making nitrogen available to plants for various biological functions. For example, nitrogen is essential for the biosynthesis of the...
01:24iChip
The cultivation of environmental microorganisms has long been hindered by the inability to replicate complex native conditions in vitro. The isolation chip (iChip) addresses this limitation by facilitating the growth of previously uncultivable microorganisms through in situ incubation. Designed for high-throughput microbial cultivation, the iChip comprises hundreds of microchambers, each capable of housing a single microbial cell. These microchambers are loaded with a mixture of molten agar and...