相关实验视频
Updated: May 10, 2026

10:33
Generation of Alginate Microspheres for Biomedical Applications
Published on: August 12, 2012
21.7K
在酸微球中封装酸乳酪,用于皮肤微生物友好的局部配方:通过设计实验方法进行优化
Elżbieta Sikora1, Anna Łętocha1, Alicja Michalczyk2
1Department of Organic Chemistry and Technology, Faculty of Chemical Engineering and Technology, Cracow University of Technology, Warszawska 24, 31-155 Cracow, Poland.
Molecules (Basel, Switzerland)
|October 16, 2025
概括
研究人员开发了酸盐微球,以从乳清中输送有益的乳酸菌细菌到护肤中. 这种益生菌输送系统保护了细菌的活力,使液体乳清在化品配方中使用成为可能.
科学领域:
- 化品科学 化品科学
- 微生物学 微生物学
- 材料科学 材料科学 材料科学
背景情况:
- 化品行业越来越多地使用对皮肤微生物友好的成分.
- 乳清中的乳杆菌细菌为皮肤健康提供益生菌的好处.
- 液体乳清在化品中的直接应用面临技术挑战.
研究的目的:
- 开发和优化酸盐微球,用于封装和输送乳清益生菌.
- 评估过程参数对微球特征和细菌生存能力的影响.
- 确认将乳清装载的微球纳入化品乳液的可行性.
主要方法:
- 利用实验设计 (DoE) 来优化酸盐微球的生产.
- 研究的变量:乳清类型,酸盐比率和超声波时间.
- 评估了封装效率,细菌存活率,粘度和微球大小.
- 将优化的微球纳入含有防腐剂的乳液中,并监测细菌活力.
主要成果:
- 确定了最佳参数:0.5分钟的超声波时间和1.5%的酸盐与乳清比率.
- 超声波照射时间是影响微球性质的最关键因素.
- 封装乳清在30天后在乳液中保持高细菌活力 (4.92 ± 0.9 log CFU/g),即使使用防腐剂.
结论:
- 酸微球有效地封装和保护乳清中的乳酸菌细菌.
- 这项技术有助于将液体乳清纳入护肤产品.
- 开发的方法支持创建稳定,富含益生菌的化品配方.
相关概念视频
Microorganisms in Agriculture and Food industry
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
Microbes in Food Production
Microbial fermentation is central to food biotechnology, enhancing flavor, texture, preservation, and stability. Fermentative microorganisms metabolize carbohydrates into organic acids, alcohols, and other metabolites that inhibit spoilage organisms and improve digestibility while contributing distinctive sensory qualities.In baking, amylases naturally present in flour hydrolyze starch into monosaccharides such as glucose, which Saccharomyces cerevisiae ferments anaerobically. Through...
Microbes in the Production of Fermented Foods
Lactic acid bacteria (LAB) and molds are instrumental in fermenting plant-based foods to enhance preservation and ensure year-round availability. These microbial processes convert plant carbohydrates into organic acids and other metabolites that inhibit spoilage organisms and contribute to the sensory qualities of the final product.In sauerkraut production, cabbage goes through a microbial succession that starts with cocci such as Leuconostoc mesenteroides. These microbes begin fermentation by...
Probiotics
Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
Production of Organic Acids
Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...
The Skin Microbiota
The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...

