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Updated: Jan 15, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
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Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

Published on: June 10, 2021

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皮佩拉津尼拉基醇/异醇类型的D3/D4选择性对抗性的结构基础

Kwang-Eun Choi1, Seong Hun Jang2, Woo-Kyu Park3

  • 1Drug Information Platform Center, Korea Research Institute of Chemical Technology, Daejeon 34114, Republic of Korea.

Molecules (Basel, Switzerland)
|October 16, 2025
PubMed
概括

设计选择性多巴胺受体配体对于治疗神经系统疾病至关重要. 这项研究使用3D-QSAR和对接来揭示结构特征,使D4受体具有选择性,有助于新药开发.

关键词:
3D-QSAR 是一个3D-QSAR.类似D2的多巴胺受体.皮佩拉齐尼基 pyrazole/isoxazole 的类似物.子类型的选择性选择性

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