和乳腺癌 (MAB) 研究:英国混合阶段,试点,安慰剂控制,双盲,随机对照试验
Lorna J Duncan1, Susan Bryant1, Gene Feder1
1Centre for Academic Primary Care, University of Bristol, Bristol BS8 2PS, UK.
Cancers
|October 16, 2025
概括
这项试点研究发现,尽管招募和注射部位反应存在挑战,但乳腺癌的脚治疗 (MT) 在英国NHS中是可行的. 合规性很好,但安全监测至关重要.
科学领域:
- 在瘤学瘤学.
- 补充医学是一种补充医学.
- 临床试验 临床试验
背景情况:
- Mistletoe疗法 (MT) 是一种补充治疗方法,用于一些乳腺癌护理.
- 它在英国国家卫生服务 (NHS) 环境中的可行性需要调查.
- 设计了一项具有定性组成部分的试点,安慰剂控制,双盲试验.
研究的目的:
- 评估一项随机对照试验 (RCT) 对乳腺癌患者的脚治疗的可行性.
- 评估NHS内部的招聘,保留,坚持,盲目和安全情况.
- 收集患者和医疗保健专业人员的定性见解.
主要方法:
- 进行了一项试点,混合阶段,安慰剂控制,双盲试验.
- 45名乳腺癌患者是NHS瘤中心招募的目标.
- 参与者接受了Iscador® Malus,Iscador® Pinus或安慰剂,可行性通过日记,问卷和采访进行评估.
主要成果:
- 14名参与者被随机分配,其中2人退出.
- 招聘挑战包括时间承诺,额外注射和安慰剂不确定性.
- 11/14名参与者经历了注射/皮肤反应;报告了22起不良事件,主要是注射相关的.
结论:
- 在英国NHS进行一项随机的安慰剂对照试验,对乳腺癌进行尾治疗是可行的.
- 确定了招募方面的挑战和患者报告的副作用 (注射,皮肤反应).
- 进一步的研究应该针对未来的大规模试验的可行性方面进行进一步研究.
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