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在小鼠结直肠和乳腺癌模型中,VSIG4对于瘤生长和转移是不可或缺的

Els Lebegge1,2, Neema Ahishakiye Jumapili1,2, Jolien Van Craenenbroeck1,2

  • 1Laboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

Cancers
|October 16, 2025
PubMed
概括

VSIG4在人体瘤相关巨细胞 (TAMs) 中表达,并与更差的预后有关. 然而,临床前模型显示,VSIG4缺乏不会影响原发性瘤生长或肝转移,这表明这些模型的局限性.

关键词:
库弗弗细胞是库弗弗细胞.在VSIG4中使用VSIG4.癌症 癌症 癌症 癌症 癌症结直肠癌结直肠癌.大的腹膜巨细胞.三重阴性乳腺癌是什么瘤微环境是一个微环境.与瘤相关的巨细胞.

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