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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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川崎病患者的中期综合心血管评估
Andréa Azar1,2, Laurie Capovilla3, Rocio Gutierrez1,2
1Division of Pediatric Cardiology, University of Montreal, CHU Sainte-Justine, Montreal, Quebec, Canada.
概括
患有冠状动脉动脉瘤的川崎病患者在诊断后多年表现出不健康的生活方式因素,包括肥胖和饮食不良. 实施量身定制的健康生活方式指南对于预防这些年轻患者心血管并发症至关重要.
科学领域:
- 心脏病学 心脏病学
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 川崎病 (KD) 是儿童获得心脏病的主要原因.
- 冠状动脉动脉瘤 (CAA) 是KD的一个重大并发症,需要采取预防策略.
- 生活方式因素在心血管健康和疾病预防方面发挥着关键作用.
研究的目的:
- 调查KD患者与没有CAA之间的生活方式差异.
- 为了确定与KD幸存者的CAA发展相关的风险因素.
- 为KD患者制定有针对性的生活方式干预措施提供信息.
主要方法:
- 对有CAA (KD-A) 和没有CAA (KD-N) 的KD患者,加上对照组 (CTL) 的横截面研究.
- 评估人体测量测量,生物化学数据,营养摄入量和体力活动5-10年后KD.
- 分析包括年龄调整的测量和3个月的食物频率问卷.
主要成果:
- 与KD-N和CTL相比,KD-A患者的超重/肥胖患病率显著更高.
- 与KD-N和CTL相比,KD-A患者的C反应蛋白 (CRP) 水平升高.
- KD-A和KD-N患者表现出过多的脂质和糖的摄入量,而KD-A参与的体力活动较少.
结论:
- 结核病患者,特别是CAA患者,在诊断后5-10年表现出生活方式偏差.
- 这些偏差增加了对严重心脏并发症的易感性.
- 实施适应社会经济环境的健康生活方式指南对于管理KD幸存者的心血管风险至关重要.
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