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Updated: Jan 15, 2026

In Vivo Proximity Biotinylation for Protein Interaction Studies in Paramecium tetraurelia
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在Paramecium中,PRC2的一个基因组甲基转移酶独立的功能控制了小RNA动力学在编程DNA消除过程中

Caridad Miró-Pina1, Olivia Charmant1, Marina Giovannetti1

  • 1Université Paris Cité, CNRS, Institut Jacques Monod, Paris F-75013, France.

Nucleic acids research
|October 16, 2025
PubMed
概括

小RNAs (scnRNAs) 指导PIWI蛋白在真核生物中使可转移元素 (TE) 沉默. 在Paramecium中,聚合体抑制复合体2 (PRC2) 选择性地降解非TE scnRNA,确保TE沉默.

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