针对手臂间血压差异与亚临床器官损伤之间的关联:帕梅拉研究的发现
Cesare Cuspidi1, Rita Facchetti1, Fosca Quarti-Trevano1
1Department of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy.
American journal of hypertension
|October 16, 2025
概括
血压中臂间差异 (IAD) 的升高与左心室缩 (LVH) 有关,这表明潜在的心脏损伤. 这一发现表明,IAD可能作为亚临床心脏问题的临床标志物.
科学领域:
- 心脏病学 心脏病学
- 高血压研究 高血压研究
- 血管健康 血管健康
背景情况:
- 在社区环境中,关于双臂间血压差异 (IAD) 和亚临床心血管损伤之间的关联存在有限的数据.
- 压力监测和他们的协会 (PAMELA) 研究调查了这种关系.
研究的目的:
- 检查手臂间血压差异 (IAD) 与亚临床心脏和血管损伤之间的关联.
- 评估IAD的患病率及其与左心室缩 (LVH) 和心脚血管指数 (CAVI) 的相关性.
主要方法:
- 该研究分析了PAMELA研究第三次调查中的527名参与者的数据.
- 测量包括病史,人体测量,血液测试,办公室血压,同时内置血管,心声和CAVI.
主要成果:
- 在66 ± 10岁的队列中观察到12%的系统性IAD (≥10 mmHg) 患病率.
- 患有左心室缩症 (LVH) 的参与者显示异常IAD的患病率显著更高 (21.7%vs10.2%).
- 在IAD和CAVI之间没有发现任何显著的关联,这是一种血管硬度的衡量标准.
结论:
- 臂间血压差异升高 (IAD) 是左心室缩 (LVH) 的潜在指标.
- LVH反映了心血管风险因素负担的增加.
- 检测到IAD可能会促使临床调查亚临床心脏器官损伤.
相关概念视频
Measurement of Blood Pressure
2.7K
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
2.7K
Hypertension III: Clinical Manifestations and Diagnostic Studies
465
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
465
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
349
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
349
Blood Pressure
9.4K
The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
9.4K
Pre-Procedural Guidelines for Assessing Blood Pressure
811
Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
811
Special considerations while measuring blood pressure
1.2K
When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
1.2K


