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血类树突细胞调节IgA粘膜IgA在IgA脏病中的产生

Yusuke Fukao1, Hitoshi Suzuki1,2, Yoshihito Nihei1

  • 1Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
|October 16, 2025
PubMed
概括

粘膜等离子细胞状树突细胞 (pDCs) 通过托尔类受体9 (TLR9) 信号传递促进IgA脏病 (IgAN) 中免疫球蛋白A (IgA) 的异常糖化. 降低pDCs降低异常IgA的产生,这表明pDCs是IgAN的治疗点.

关键词:
4月份的时间.在Gd-IgA1A1中.在IgA脏病发作中,IgA脏病发作在TLR9中,血细胞状的树突细胞细胞.

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