从城市娱乐湖探索水,沉积物和鸟类:专注于世卫组织优先病原体
Mateus Rocha Ribas1, Juliana Lemos Dal Pizzol1, Gustavo Rocha1
1Laboratório de Microbiologia Molecular Aplicada (MiMA), Departamento de Análises Clínicas, Centro de Ciências da Saúde, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, 88036-800, Brazil.
Journal of applied microbiology
|October 16, 2025
概括
在巴西,抗菌素耐药性 (AMR) 正在扩散.
科学领域:
- 环境微生物学环境微生物学
- 一个健康 一个健康
- 抗微生物耐药性 (AMR) 是一种
背景情况:
- 抗微生物耐药性 (AMR) 病原体是一个全球性问题.
- 沿海生态系统是AMR的研究不足的水库.
- 巴西的沿海湖是生物多样性和受影响的人类活动.
研究的目的:
- 评估巴西Lagoa da Conceição的AMR细菌的发生和分布.
- 确定世卫组织在水,沉积物和鸟类中的关键优先病原体.
- 调查影响AMR传播的环境因素.
主要方法:
- 收集了96个环境和251个鸟类样本 (2022年12月-2023年11月).
- 使用选择性培养,抗菌素敏感性测试和分子查.
- 使用通用线性模型分析数据.
主要成果:
- 35.5%的分离物是多药耐药的; 26.7%符合世卫组织的关键优先级标准.
- 确定了关键的耐药性基因 (blaTEM,blaCTX-M,blaNDM,blaOXA-143,mcr-1).这些基因的作用是:
- 世卫组织在9.6%的鸟类中发现了关键优先病原体;与人口密度和降水量有关.
结论:
- 人类和气候因素导致沿海地区的AMR.
- 鸟类动物作为防护和储存AMR病原体的哨兵.
- 综合监测和缓解对生态系统和公共健康至关重要.
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