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Updated: Jan 15, 2026

Measurement of Natural Killer Cell-Mediated Cytotoxicity and Migration in the Context of Hepatic Tumor Cells
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RNA螺旋酶DDX3X通过支持MCL1表达来促进NK细胞的生存

Eshana Mukhopadhyay1,2, Nora Lakes2,3,4, Durga Krishnamurthy2

  • 1Development, Stem Cells, and Regenerative Medicine Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, United States.

Journal of immunology (Baltimore, Md. : 1950)
|October 16, 2025
PubMed
概括

死亡盒RNA螺旋酶DDX3X对于自然杀手 (NK) 细胞的生存至关重要. 它通过增强生存蛋白MCL1.1的翻译来支持NK细胞的维持.

关键词:
这是一种RNA结合蛋白.灭症 (apoptosis) 是一种死亡的过程.恒常状态 (homeostasis) 是一种平衡状态.天生的淋巴细胞是先天性淋巴细胞.

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