螺旋断层疗法CT-to-mass-density转换表的机构间变异性:日本的一项全国性调查
Shogo Tsunemine1, Shuichi Ozawa2, Ryosei Nakada1
1Department of Radiation and Proton Office, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka 411-8777, Japan.
Journal of radiation research
|October 16, 2025
概括
这项研究发现,在螺旋式断层疗法中使用的计算机断层扫描数量密度 (CT-MD) 表中存在显著差异,突出了标准化的需要. 实施一致的幻体几何和质量保证协议可以提高适应性放射治疗 (ART) 中的剂量准确性.
科学领域:
- 医学物理 医学物理
- 放射治疗技术 放射治疗技术
- 基于图像的质量保证
背景情况:
- 计算机断层扫描数量-质量密度 (CT-MD) 转换表对于螺旋式断层疗法中准确的剂量计算至关重要.
- 随着适应性放射治疗 (ART) 的日益普及,需要一致可靠的CT-MD表.
- 在CT-MD表生成实践中,机构间的差异对剂量准确性提出了挑战.
研究的目的:
- 评估目前在日本CT-MD表生成螺旋式断层疗法的实践和挑战.
- 探索CT-MD表格的标准化和质量改进的方向,特别是对于ART.
- 评估不同CT模式 (SimCT,ClearRT,CTrue) 和校准方法之间的差异.
主要方法:
- 在34个使用Radixact系统的机构中进行了全国性的基于网络的调查.
- 收集的数据包括CT采集协议,校准幻象,重建算法和质量保证 (QA) 频率.
- 基于CT模式,幻影设置 (全对半) 和重建方法 (FPB对IR) 分析了CT-MD表.
主要成果:
- 在CT数量和SimCT表的数据点数量中观察到显著的机构间差异.
- 清晰RT表显示了变化,但半幻设置减少了机构间的变化.
- CTrue表显示出很高的一致性,尽管气塞CT数量有所不同,而43%的机构缺乏常规的QA.
结论:
- 标准化幻影几何,空气CT号码处理和质量保证协议对于改善CT-MD表的一致性至关重要.
- 使用半幻校准设置可能会减少ClearRT表中的变化.
- 一致的CT-MD表对于确保适应性放射治疗中剂量准确性至关重要.
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