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相关实验视频

Updated: Jan 15, 2026

Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model

Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model

Published on: November 19, 2017

实时自适应时间序列细分算法的硬件实现,用于皮内植入物.

Gabriel Galeote-Checa, Gabriella Panuccio, Bernabe Linares-Barranco

IEEE transactions on biomedical circuits and systems

|October 16, 2025

概括

一个新的时间序列分割 (TSS) 算法可以在神经植入物中实现设备内发作检测,从而改善管理. 这种方法减少了数据传输需求和长期使用的功耗.

科学领域:

生物医学工程生物医学工程
神经科学是一个神经科学.
信号处理信号处理

背景情况:

影响全球超过5000万,许多患者对标准治疗没有反应.
带有设备内算法的神经植入物提供先进的实时发作检测,减少数据传输负担.
植入物中电极数量的增加需要高效的处理来管理数据和电力,以实现长期可行性.

研究的目的:

引入一种新的时间序列分割 (TSS) 算法,用于从原始神经记录中提取标记信息.
开发一种高效的设备处理系统,用于植入性管理设备.
提高发作检测的准确性,并使局部现场潜能 (LFP) 的临床解释成为可能.

主要方法:

使用时间序列细分 (TSS) 具有异常值检测和启发式事件分类器.
实施多道共识策略,通过多道协议提高检测准确性.
在微电极阵列 (MEA) 上测试了算法,该算法来自于经过4 - 氨基胺处理的小鼠海马皮层切片的记录.

主要成果:

该系统实现了高性能发作检测,并将LFP细分为临床相关的标签.
在实验数据上证明了强大的可靠性.
在Pynq-Z2电路板上实现了95%的准确性,94%的灵敏度和0.03%的假阳性率 (FPR),功耗为128兆瓦.

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The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice

The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice

Published on: July 26, 2024

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Published on: March 31, 2023

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Last Updated: Jan 15, 2026

Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model

Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model

Published on: November 19, 2017

The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice

The DREAM Implant: A Lightweight, Modular, and Cost-Effective Implant System for Chronic Electrophysiology in Head-Fixed and Freely Behaving Mice

Published on: July 26, 2024

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Subdural Soft Electrocorticography ECoG Array Implantation and Long-Term Cortical Recording in Minipigs

Published on: March 31, 2023

结论:

开发的TSS算法在可植入神经设备的设备内处理方面是有效的.
这种方法通过实现高效的实时发作检测,推进了个性化的治疗.
该系统提供了一种低功耗,高精度的解决方案,用于管理先进的神经植入物的日益增长的数据需求.