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Updated: Jan 15, 2026

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与向PCR丰富和读取映射相关的SARS-CoV-2测序文物

Kirsten Maren Ellegaard1, Vithiagaran Gunalan2, Raphael Sieber1

  • 1Department of Sequencing and Bioinformatics, Statens Serum Institut, Copenhagen, Denmark.

PloS one
|October 16, 2025
PubMed
概括

初始选择和参考基因组选择显著影响SARS-CoV-2基因组测序的准确性. 持续监测和更新原料方案和生物信息管道对于可靠的变种监测至关重要.

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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