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通过非侵入性口腔微核测定,评估长期暴露在油漆中的DNA损伤

İzem Bilinmiş1, Senanur Durna1, Sultan Pınar Çetintepe2

  • 1Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Başkent University, Ankara, Türkiye.

Toxicology and industrial health
|October 16, 2025
PubMed
概括

涂料工人显示DNA损伤增加,特别是那些在生产和长期暴露. 这种职业基因毒性强调了在涂料行业需要进行健康监测的必要性.

关键词:
造成的DNA损伤是DNA损伤.油漆工人 油漆工人 油漆工人 油漆工人对DNA损伤的生物监测.在口腔的微核.职业暴露 职业暴露 职业暴露

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Nucleotide Excision Repair01:38

Nucleotide Excision Repair

DNA Distortion and Damage
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...