灵活的可穿戴水凝贴片与"海绵状"纤维素SERS芯片集成,用于尿素和乳酸的汗水分析
Haonan Wang1, Qingling Nie2, Luyao Lin2
1Fuzhou Hospital of Traditional Chinese Medicine, 350001, China; College of Chemistry and Materials Science, Fujian Provincial Key Laboratory of advanced Oriented Chemical Engineer, Fujian Key Laboratory of Polymer Materials, Engineering Research Center of Industrial Biocatalysis, Fujian Province Higher Education Institutes, Fujian Normal University, Fuzhou, Fujian, 350007, China.
Talanta
|October 16, 2025
概括
这项研究引入了一种用于可穿戴传感器的新型水凝贴片,增强了绿色传感技术. 灵活的贴片提供了卓越的粘附性,生物相容性和抗菌性质,用于个性化的医疗监测.
科学领域:
- 生物材料科学 生物材料科学
- 可穿戴技术可穿戴技术
- 绿色化学 绿色化学
背景情况:
- 在纤维素和水凝的进步使绿色可穿戴感应.
- 现有的可穿戴传感器需要提高皮肤附着性和生物相容性.
研究的目的:
- 开发一种用于皮肤粘附可穿戴传感器的新型柔性水凝贴片.
- 整合水凝和多孔技术,以提高传感器性能.
主要方法:
- 合成了一种由烯胺和氨酸盐组成的复合凝,经酸修饰.
- 为SERS检测设计了一种硫化纤维素纳米纤维/藻酸盐/银纳米粒子 (S-CNF/SA/Ag NPs) 膜.
- 评估了机械性能,生物相容性,抗菌疗效和表皮粘附.
主要成果:
- 复合水凝显示出出色的机械强度,生物相容性 (98.75%的细胞活力) 和抗菌活性 (92.03%的抑制).
- 该S-CNF/SA/Ag NPs模块实现了对汗液生物标记物的高灵敏度 (尿素: 10−6 M,乳酸: 10−5 M).
- 该贴片表现出优越的表皮形状和持续的粘附性.
结论:
- 开发的水凝贴片是先进的可穿戴生物传感的有希望的平台.
- 这项技术支持个性化医疗保健,运动生理学和诊断方面的应用.
- 这项研究加速了绿色可穿戴生物传感平台的创新.
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