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中国老年人手握强度与认知功能之间的纵向双向动态关联:一个交叉滞后建模研究
Xuan Zhang1, Chenxiao Jia1, Haixia Hao1
1Department of Medical Statistics and Epidemiology, School of Public Health, Tianjin Medical University, 300070 Tianjin, China.
Archives of gerontology and geriatrics
|October 16, 2025
概括
拥有更强握力的老年人保持更好的认知功能,反之亦然. 这种双向肌肉认知联系在男性和70-79岁的人群中更强,为预防认知衰退提供了针对性的干预措施.
科学领域:
- 老年学和认知神经科学
- 公共卫生与衰老研究 公共卫生与衰老研究
背景情况:
- 认知能力下降是全世界老龄化人口的一个重大问题.
- 了解影响老年人认知健康的因素对于开发有效的干预措施至关重要.
- 手握强度是衡量肌肉功能的一种指标,已被事地与整体健康和潜在的认知状态联系起来.
研究的目的:
- 调查60岁及以上的中国成年人手握强度和认知功能之间的动态,双向关系.
- 探索性别和年龄如何影响这种肌肉认知关联.
- 为在认知健康评估和干预中整合物理措施提供证据.
主要方法:
- 利用来自中国健康与退休长度研究 (CHARLS) 的数据,2013-2015年波.
- 采用交叉滞后面板模型来分析2年时间内手握强度和认知功能之间的时间关联.
- 在4533名老年人中控制了社会人口统计学,生活方式和健康共变量.
主要成果:
- 在2年的随访期间,手握强度和认知功能都下降了.
- 基线握手强度在随访时积极预测认知功能,基线认知功能在随访时积极预测握手强度 (双向关联).
- 观察到性别差异:男性的握手力与认知力更强,而女性的握手力与认知力更强. 这种关联在70-79岁年龄组中最为强烈.
结论:
- 在老年人中,肌肉强度 (手握) 和认知功能之间存在显著的双向关系.
- 手握强度评估可以成为老年人群认知查的一个有价值的工具.
- 干预措施应根据性别和年龄量身定制,重点关注70-79岁的农村,受教育程度较低和高风险人群,以防止认知能力下降.
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