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Updated: Jan 15, 2026

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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在糖尿病小鼠中,西塔利普丁通过激活Nrf2-SLC7A11-GPX4轴来抑制神经元铁亡,以缓解认知功能障碍

Han Meng1, Zhaoyu Xie2, Tao Xu2

  • 1Department of Pharmacology, Wannan Medical College, Wuhu 241002, China; Anhui Innovative Center for Drug Basic Research of Metabolic Diseases, Wannan Medical College, Wuhu 241002, China.

International immunopharmacology
|October 16, 2025
PubMed
概括

乙型糖尿病药物西塔格利普丁通过Nrf2通路预防脑细胞死亡 (神经元铁亡),改善了糖尿病小鼠的记忆和学习.

关键词:
糖尿病是一种糖尿病.糖尿病认知功能障碍 糖尿病认知功能障碍铁化是铁化的一种.Nrf2 没有任何问题.西塔格利普丁是如何使用的

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