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产前荷尔蒙特征 (2D:4D) 和儿童时期的牙成熟:一个前性研究

Türkan Ünal¹, Fatma Nur Kızılay², Emine Gülşen¹

¹Department of Pediatric Dentistry, Alanya Oral and Dental Health Center, Antalya, Türkiye.

Early human development

|October 16, 2025

概括

第二到第四个数字的比率 (2D:4D) 与儿童的牙成熟有很弱的相关性. 这种非侵入性标记可能为牙发育评估提供补充数据,特别是在女孩身上.

科学领域:

人类学是人类学.
儿科牙科儿科牙科
内分泌学在内分泌学.

背景情况:

第二到第四位数的比率 (2D:4D) 是产前激素暴露的标志物.
它与牙成熟的关系尚未得到充分证实.
这项研究调查了2D:4D作为牙发育的潜在生物标志物.

研究的目的:

评估2D:4D和儿童牙成熟之间的关联.
评估2D:4D作为牙发育的补充生物标志物.

主要方法:

300名儿童 (6-12岁) 进行双边2D:4D测量.
使用Demirjian的方法从全景放射图评估牙年龄.
统计分析包括相关性和多重回归,对计时年龄,性别和BMI进行控制.

主要成果:

在时间和牙科年龄之间发现了强烈的相关性 (r=0.976).
总的来说,2D:4D显示出与牙年龄的联系很弱但很显著 (右:r=0.155,左:r=0.135).
性别分层分析显示,女孩的趋势不显著,男孩没有相关性.

结论:

2D:4D与牙成熟的关系在人口层面上很弱.
这种关联在两性之间并不显著,尽管在女孩中存在趋势.
2D:4D可以作为牙发育评估的非侵入性,支持性措施.

关键词:

2D:4D比率是什么意思牙科发展牙科发展发育成熟度发育成熟度内分泌生物标志物内分泌生物标志物产前的荷尔蒙暴露产前的荷尔蒙暴露

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Teeth

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