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EEG Mu Rhythm in Typical and Atypical Development
Published on: April 9, 2014
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慢性中风中的皮质和皮质脊髓反应与异常的mu节律状态相关
Miles Wischnewski1, Zachary J Haigh2, Taylor A Berger2
1Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA; Department of Psychology, Experimental Psychology, University of Groningen, Groningen 9712TS, The Netherlands.
概括
感觉运动律的阶段会影响运动皮层的刺激性. 这种效应在中风幸存者中减弱,相位偏好减少与运动障碍严重程度相关.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 康复 康复 康复 康复
背景情况:
- 运动皮层活动取决于状态,传感运动mu节奏阶段影响健康个体的初级运动皮层 (M1) 兴奋度.
- 这种关系对患有中风相关脑损伤的个体的概括性仍然未被探索.
研究的目的:
- 在中风幸存者中调查mu振荡和皮质刺激性之间的相位关系.
- 为了确定这种关系是否在中风幸存者和健康对照者之间有所不同.
主要方法:
- 结合实时电脑电图 (EEG) 和M1.1的跨磁刺激 (TMS).
- 在23名参与者 (中风幸存者和健康对照) 中,在Mu振荡的四个阶段应用了TMS.
- 测量了发动机引起的 (MEP) 和TMS引起的电位 (TEP) 振幅.
主要成果:
- 在中风幸存者和老年人中,MEP的幅度显示出相位依赖性,mu节律低谷时的MEP增加.
- 在具有更严重运动症状的个体中观察到相位偏好的减少.
- 与未受影响半球相比,中风影响半球中TEPs的相位依赖性减少了.
结论:
- TMS运动反应阶段偏好的强度可能表明中风后的运动损伤严重程度.
- 这些发现可能有助于开发用于运动恢复的增强的TMS范式.
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