在安全网医疗保健系统服务的无症状患者中,Helicobacter pylori感染的血清流行率
Aaron P Thrift1, Peyman Dinarvand2, Luis Juarez3
1Section of Epidemiology and Population Sciences, Department of Medicine, Baylor College of Medicine, Houston, Texas; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas.
概括
在美国高危人群中,近三分之二的无症状个体检测出Helicobacter pylori (H. pylori) 感染阳性. 这种高血清发病率强调了在服务不足的社区进行有针对性的h pylori查的必要性,以预防胃癌.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 查和根除Helicobacter pylori (H. pylori) 是有效的预防高风险人群的胃癌.
- 对于美国高风险群体,特别是低收入和没有保险的个人,有有限的基于人口的H pylori血清流行数据.
研究的目的:
- 为了确定H pylori的血清流行率在一个基本上服务不足,移民和少数美国患者群体中.
- 在这个人口群体中识别H pylori感染风险因素.
主要方法:
- 一项涉及1021名30-65岁无症状成年人的横截面研究,没有先前接受过H pylori治疗.
- 通过调查和IgG血清学血液检测H. pylori收集的数据.
- 血清患病率计算为整体和按人口分组计算.
主要成果:
- 在研究人群中,总体H pylori血清流行率为63.9%.
- 血清发病率在男性 (69.1%) 比女性 (61.6%) 高,在西班牙裔个人 (65.9%) 和出生在中美洲的人 (75.1%) 中最高.
- 在所有子组中,患病率超过40%,第二代和第三代移民之间没有差异.
结论:
- 在这个服务不足的人群中,绝大多数无症状的个体对H. pylori有阳性.
- 仅基于种族/种族的查可能会因为社会经济地位和区域暴露等混因素而错过有风险的个体.
- 针对性H pylori查对于在多样化,高风险的美国人群中预防胃癌至关重要.
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