帕金森病患者血液细胞中DNA甲基转移酶1水平降低

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A O Lavrinova1, E M Litusova1, P A Gagarina1

  • 1Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», mkr. Orlova roshcha, 1, Gatchina, 188300, Russia.

Neuroscience
|October 16, 2025
PubMed
概括

帕金森病 (PD) 与减少的DNA甲基转移酶1 (DNMT1) 蛋白水平和血液细胞中的全球DNA低甲基化有关. 在PD患者中也观察到高水平的α-synuclein,这表明表观遗传变化在疾病发病过程中的作用.

关键词:
阿尔法-同核素是什么阿尔法-同核素血细胞是血液中的细胞.基因甲基转移酶1 (DNMT1) 是一种DNA甲基转移酶.多巴胺是一种多巴胺.全球DNA甲基化帕金森病是帕金森氏症的一种疾病.

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