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Updated: Jan 14, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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非白血病原体体点突变的遗传决定因素和基因组后果

Joshua S Weinstock1, Sharjeel A Chaudhry2,3, Maria Ioannou4

  • 1Department of Human Genetics, School of Medicine, Emory University, Atlanta, GA, USA. josh.weinstock@emory.edu.

Nature communications
|October 16, 2025
PubMed
概括

没有已知的突变 (CH-LPMneg) 的克隆性血液形成是常见的. 一种名为GEM的新方法量化了突变负担,并揭示了遗传,基因组和表型联系,包括与白细胞计数的关联.

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