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Updated: Jan 14, 2026

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表观遗传改变在缺氧中促进了转录和翻译程序

Kathleen Watt1,2, Bianca Dauber2, Krzysztof J Szkop1

  • 1Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.

Nature cell biology
|October 16, 2025
PubMed
概括

细胞应激适应涉及基因表达的变化. 这项研究揭示了表观遗传重编程,特别是H3K4me3调制,改变了转录起点 (TSS) 并在缺氧期间增强了蛋白质合成.

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