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由于MC4R缺乏而导致的肥胖与降低胆固醇,甘油三和心血管疾病风险相关

Stefanie Zorn1,2, Rebecca Bounds1, Alice Williamson3,4

  • 1University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.

Nature medicine
|October 16, 2025
PubMed
概括

大脑黑色皮质素4受体 (MC4Rs) 的缺陷降低了人类的胆固醇和甘油三,降低了心血管疾病的风险. 这表明MC4Rs是脂质代谢和心脏健康的关键调节者.

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