绘制地图以估计健康状态的实用性:对发展和局限性的系统审查
Qiang Su1, Xiaochen Peng1,2, Yumeng Zhang1
1Department of Pharmacy Administration, School of Business Administration, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, Liaoning Province, 110016, People's Republic of China.
Health and quality of life outcomes
|October 17, 2025
概括
地图研究对于成本效益分析至关重要,但面临着挑战. 最近在样本大小和模型方面有所改进,但概念重叠和区域调整的问题仍然存在,需要更新指南.
科学领域:
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
- 研究结果研究成果.
背景情况:
- 健康效用测量对于成本效益分析 (CUA) 是至关重要的.
- 临床研究中常常缺少直接效用数据,因此需要像绘图这样的间接方法.
- 现有的绘图方法面临挑战,并且在不同研究中存在差异.
研究的目的:
- 系统地审查当前的景观,趋势和健康实用地图研究的局限性.
- 为改善绘图研究的设计和报告标准提供建议.
主要方法:
- 在PubMed,科学网和HERC地图研究数据库 (2018-2024) 中进行了全面的文献搜索.
- 信息提取和质量评估是根据已建立的映射准则进行的.
主要成果:
- 包括131项研究,其中92项专注于绘制地图作为主要目标.
- EQ-5D和EORTC-QLQ-C30是常见的措施,普通最小平方 (OLS) 是主要的模型.
- 虽然样本大小和模型多样性增加,但仍然存在重大局限性,包括缺乏概念重叠分析和不一致的区域价值集.
结论:
- 近年来,绘图研究在样本大小,模型应用和报告方面取得了进展.
- 持续存在的挑战包括概念重叠分析,样本和值集的区域对齐以及处理重复测量.
- 更新绘图指南和确保合规对于提高未来绘图研究的质量至关重要.
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