血液透析患者的认知衰退:使用阿登布鲁克的认知检查-III (ACE-III) 的横截面研究
Siri Chandana1, Jayakumar M1, Sandhya Suresh1
1Department of Nephrology, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Cureus
|October 17, 2025
概括
认知障碍影响南印度近一半的血液透析患者,特别影响记忆力和注意力. 建议使用ACE-III进行早期查,以及时干预慢性病护理.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 神经学 神经学
- 心理学 心理学 心理学
背景情况:
- 认知障碍 (CI) 是一种常见的,经常未被诊断的并发症,患者接受维护血液透析 (HD).
- 了解像南印度这样多样化的人口中CI的流行率和模式对于有效的管理至关重要.
- 阿登布鲁克的认知检查-III (ACE-III) 为评估认知功能提供了一个全面的工具.
研究的目的:
- 确定在维护血液透析的南印度患者中认知功能障碍的患病率和模式.
- 确定与该人口认知障碍相关的临床和社会人口统计因素.
- 评估ACE-III对查HD患者认知障碍的有用性.
主要方法:
- 一项涉及印度泰米尔纳德邦奈市175名维护血液透析患者的横截面研究.
- 用阿登布鲁克认知检查-III (ACE-III) 的印度英语版本来评估认知功能.
- 收集和分析了关于年龄,性别,教育,透析持续时间,并发病症和血红蛋白水平的数据.
主要成果:
- 在46.9% (175人中82人) 的患者中发现认知障碍,ACE-III分数在60-80.0之间.
- 较低的认知分数与年龄较大,教育程度较低和透析持续时间较长 (p<0.05) 有显著的相关性.
- 记忆和注意力领域最常受到认知功能障碍的影响.
结论:
- 认知障碍在南印度血液透析患者中非常普遍,与年龄,教育和透析持续时间有显著的关联.
- 使用ACE-III的常规查可以帮助在血液透析患者中早期检测认知障碍.
- 基于早期检测的有针对性的干预措施可以改善慢性病患者进行透析的认知功能障碍的结果.
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