相关实验视频

Updated: Jan 14, 2026

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation

Published on: October 15, 2021

慢性亚皮血瘤治疗与栓塞与手术研究 (CHESS):试验理由和协议

Manisha Koneru¹, Ajith J Thomas¹, Farhan Siddiq²

¹Department of Neurosurgery, Cooper University Health Care, Camden, NJ, USA.

International journal of cerebrovascular disease and stroke

|October 17, 2025

概括

该CHESS试验将独立的中脑膜动脉栓塞 (MMAE) 与慢性腹腔内血瘤 (CSDH) 的手术进行比较. 本研究旨在确定MMAE作为安全有效的CSDH独立治疗方法.

科学领域:

神经外科神经外科
干预性神经辐射学
临床试验临床试验

背景情况:

慢性亚皮血瘤 (CSDH) 通常通过药物或手术进行管理.
中脑膜动脉栓塞 (MMAE) 显示出减少CSDH复发和需要救援手术的希望.
在CSDH治疗中缺乏独立MMAE随机对照试验数据.

研究的目的:

为了比较独立的MMAE与用于治疗中度症状的CSDH的常规手术.
评估MMAE作为独立的CSDH治疗的安全性和有效性.
为推进CSDH管理中的内血管方法提供数据.

主要方法:

未来的,多中心的,开放标签的随机对照试验 (CHESS研究).
随机化CSDH患者1:1进行传统手术或独立MMAE.
180天的随访期来评估结果.

主要成果:

主要终点:复合的救援手术和/或死亡180天内.
评估的安全结果:缺血性中风,不良事件,神经状态,发作,脑神经病变.
探索性终点:血瘤体积减少,功能结果,生活质量,认知,头痛严重程度.

结论:

CHESS是第一个评估独立MMAE与中度CSDH常规手术的RCT.
结果将告知内血管技术在CSDH治疗中的作用.
这项试验解决了在CSDH管理中MMAE证据的关键缺口.

关键词:

慢性腹膜下血腫慢性腹膜下血腫临床试验临床试验是指临床试验的临床试验.血栓形成的过程中发生了栓塞.血管内脏手术血管内脏手术处理分析的意图.试验协议试验协议进行了骨切除术 (craniotomy).

更多相关视频

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model

Published on: June 18, 2021

相关概念视频

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...