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Updated: Jan 14, 2026

Bio-layer Interferometry for Measuring Kinetics of Protein-protein Interactions and Allosteric Ligand Effects
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Bio-layer Interferometry for Measuring Kinetics of Protein-protein Interactions and Allosteric Ligand Effects

Published on: February 18, 2014

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前所未有的全抑制E.E. 大肠杆菌酸脱酶由银 (从原子分辨率分析中)

Haibo Wang1, Minji Wang2, Xinming Yang1

  • 1Department of Chemistry and HKU-CAS Joint Laboratory of Metallomics on Health and Environment, The University of Hong Kong Pokfulam Road Hong Kong P. R. China hsun@hku.hk.

Chemical science
|October 17, 2025
PubMed
概括

银离子 (Ag+) 通过向酸脱酶 (MDH) 来抑制细菌生长. 这项研究揭示了Ag+与MDH的结合如何导致形状变化,阻断酶活性并提供新的抗生素点.

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Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

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Enzyme Inhibition01:30

Enzyme Inhibition

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Formation of Complex Ions

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