长期COVID患者中常见症状的发生率和持续时间:系统性审查和元分析
Siyi Luo1, Lana Yh Lai2, Rui Zhu3
1Department of Acute Infectious Disease Prevention and Control, Kunming Center for Disease Control and Prevention, Kunming, Yunnan, China.
Journal of global health
|October 17, 2025
概括
长期COVID症状经常在感染后持续存在,影响日常生活. 这篇评论详细介绍了常见的持续症状,如疲劳和认知问题,为长期的COVID管理提供了见解.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在COVID-19后持续的症状,称为长期COVID,显著影响患者的日常生活和健康.
- 了解长期COVID的长期影响对于患者护理和公共卫生战略至关重要.
- 为了解决这一知识差距,进行了系统审查和元分析.
研究的目的:
- 系统地识别,评估和总结COVID-19急性阶段后持续症状的发生率和持续时间.
- 确定长期COVID对患者健康和日常功能的长期影响.
- 为预防和治疗COVID后疾病提供基线数据.
主要方法:
- 在PubMed,Embase和medRxiv上进行了系统的文献搜索,直到2021年8月.
- 在基于PICOS框架和使用纽卡斯尔-太华尺度进行偏差评估的查后,包括了19项观察性研究.
- 用元分析来确定常见的长期COVID症状的患病率和持续时间.
主要成果:
- 认知/记忆/注意力障碍在36%的未报告持续时间的病例中被报告.
- 疲劳 (34%,5.5个月),精神健康问题 (31%,3.5-3.8个月),呼吸障碍 (24%,6.52个月) 和胸痛 (23%,2个月) 也是常见的持续症状.
- 确定了五种常见的长期COVID症状的发生率和持续时间.
结论:
- 长期COVID症状通常会持续到COVID-19的急性阶段之后.
- 确定的症状集群为研究后COVID疾病的病因学,诊断和管理提供了方向.
- 该研究提供了必要的基线数据,用于制定有效的预防和治疗长期COVID的策略.
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