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对Cry1B.34.1,Cry1B.61.1和IPD083Cb蛋白对非目标生物的环境风险评估

Joseph E Iboyi¹, Chad J Boeckman¹, Kristine LeRoy¹

¹Regulatory and Stewardship, Corteva AgriscienceTM, Johnston, Iowa, USA.

GM crops & food

|October 17, 2025

概括

新的转基因大豆COR23134,表达Bacillus thuringiensis (Bt) 和新型杀虫蛋白,对非标生物 (NTO) 构成的风险可以忽略不计. 环境风险评估证实了它对于大豆生产中的可持续害虫管理的安全性.

科学领域:

农业科学农业科学
昆虫学昆虫学是一门学科.
生物技术是生物技术.

背景情况:

虫害威胁着全球大豆生产,对当前的害虫管理策略,如Bacillus thuringiensis (Bt) 作物等作物产生耐药性.
发现具有新作用模式的新型杀虫蛋白对于农业中可持续和持久的害虫控制至关重要.

研究的目的:

评估COR23134大豆所带来的环境风险,该大豆表达Bt衍生物蛋白 (Cry1B.34.1,Cry1B.61.1) 和一种新的植物衍生物蛋白 (IPD083Cb).
评估这些杀虫蛋白在培养过程中对非标生物 (NTOs) 的安全性.

主要方法:

环境风险评估包括I级实验室危险研究.
将研究结果与估计的环境度 (EEC) 进行比较,以确定暴露率 (MOE).
对Cry1B.34.1,Cry1B.61.1和IPD083Cb蛋白在COR23134大豆中的暴露和危害的评估.

主要成果:

对表达的杀虫剂蛋白质计算了暴露率 (MOE) 值的边际.
对Cry1B.34.1,Cry1B.61.1和IPD083Cb蛋白进行了暴露和危害评估.
这些蛋白质的环境现实度对NTO种群没有表现出不合理的不良影响.

结论:

在COR23134大豆中表达的杀虫蛋白在现实的环境度下对NTOs是安全的.
种植COR23134大豆被认为对非目标生物体的风险是可以忽略不计的.
这种转基因事件通过提供额外的行动方式来支持可持续的害虫管理,以对抗类害虫.

关键词:

COR23134 大豆的使用情况在 Cry1B.34.1 中.在Cry1B.61.11.1中使用.在IPD083Cb中,我们可以使用IPD083Cb.环境风险评估环境风险评估风险暴露风险暴露风险暴露转基因作物是一种转基因作物.危险的危险性危险的危险性非目标生物的非目标生物.

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