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Updated: Jan 14, 2026

Characterization of Synthetic Polymers via Matrix Assisted Laser Desorption Ionization Time of Flight MALDI-TOF Mass Spectrometry
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Published on: June 10, 2018

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基于残留的热重力测量分析:一种新的方法来量化宏分子中碳酸盐组的变化

Christos Leliopoulos1, Hamidreza Mokhtari1, Shima Tavakoli1

  • 1Translational Chemical Biology Laboratory, Division of Macromolecular Chemistry, Department of Chemistry-Ångström Laboratory, Uppsala University, Uppsala Se75121, Sweden.

Biomacromolecules
|October 17, 2025
PubMed
概括

一种新的热重力测量分析 (TGA) 方法准确量化了氨酸 (HA) 修饰的数量. 这种基于残留的技术适用于各种HA衍生物,甚至是以前无法量化的衍生物,推动了生物材料的开发.

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Carboxylic acids, upon heating, undergo a decarboxylation reaction by releasing carbon dioxide gas. Monocarboxylic acids do not undergo decarboxylation easily. However, a silver salt of carboxylic acid reacts with bromine or iodine under high temperature to release carbon dioxide gas and forms halide with one less carbon. This reaction is called the Hunsdiecker reaction.
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Oxidation of aldehydes and ketones results in the formation of carboxylic acids. Aldehydes, bearing hydrogen next to the carbonyl group, are easily oxidized compared to ketones. This is because an aldehydic proton can easily be abstracted during oxidation.
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