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初级皮肤T细胞淋巴瘤的组织病理谱:来自越南病例系列的见解

Giang H Tran^1,2, Tu T Nguyen², Khoa A Luong²

¹Department of Histology, Embryology, and Pathology, School of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam ; and.

The American Journal of dermatopathology

|October 17, 2025

概括

这项研究描述了越南的原发性皮肤T细胞淋巴瘤 (PCTCL),发现皮下泛肠炎类T细胞淋巴瘤最常见. 与西方数据的差异凸显了该地区改善诊断和护理准入的需要.

科学领域:

皮肤病学皮肤病学
血液学血液学血液学
在瘤学瘤学.

背景情况:

初级皮肤T细胞淋巴瘤 (PCTCL) 是一种罕见的外节淋巴瘤,东南亚的数据有限.
了解不同人群中的PCTCL对于准确的诊断和治疗至关重要.

研究的目的:

调查越南患者中PCTCLs的临床,组织病理和免疫组织化学特征.
将发现与国际数据进行比较,并确定区域特点.

主要方法:

对来自越南的39例PCTCL病例进行了回顾性分析.
对人口统计,临床,组织病理学和免疫组织化学数据的审查.
分类符合世卫组织血液淋巴瘤分类 (第5版) 的分类. ) 的情况.

主要成果:

皮下泛炎样T细胞淋巴瘤是最常见的亚型 (36%).
菌根性菌病 (MF) 和一次性皮肤形大细胞淋巴瘤 (pcALCL) 呈现出不同的年龄分布.
在多发性肺炎中,发现了高率的Pautrier微和eosinophilic透.

结论:

越南PCTCL的特点在很大程度上符合全球标准,但显示出显著的差异.
差异可能源于诊断延迟,转诊偏差和诊断资源有限.
加强临床病理整合和获得专业护理是必不可少的.

关键词:

临床表现临床表现组织病理学组织病理学免疫组织化学免疫组织化学原发性皮肤T细胞淋巴瘤

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