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Updated: Jan 6, 2026

Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS
09:20

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Published on: August 10, 2017

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一个双CYP17A1/HDAC6抑制剂,用于针对性前列腺癌治疗

Hoang Yen Tran1,2, Chien-Liang Lin3, Hong-Yi Lin4,5

  • 1School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|October 17, 2025
PubMed
概括

一种新药物MPT1A160有效地准了雄激素受体 (AR) 信号和表观遗传调节. 这种双重抑制策略在克服前列腺癌的治疗耐药性方面表现有希望,前列腺癌是男性癌症死亡的主要原因.

关键词:
在AR信号传输方面.化学电阻是一种化学电阻.它具有双重CYP17A1/HDAC6抑制作用.表观遗传调节 表观遗传调节前列腺癌是前列腺癌.

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