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总结与感官风险因素相关的痴呆症患病率的可归因人口比例
Jason R Smith1,2, Xi Wang1,2, Wuyang Zhang1,2
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Journal of Alzheimer's disease : JAD
|October 17, 2025
概括
听力和视力损失等可治疗的感官障碍与老年人中超过一半的痴呆病例有关. 解决这些感官问题可以显著帮助全国的痴呆症预防工作.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 神经科学是一个神经科学.
背景情况:
- 听力和视力损失被确定为痴呆症可治疗的感官风险因素.
- 具有全国代表性的估计对于制定有效的老年痴呆症预防策略至关重要.
研究的目的:
- 估计因可治疗的感官风险因素 (听力和视力损失) 而导致的痴呆病发病率的比例.
- 分析这些关联在不同年龄组,种族/种族背景,收入水平和性别之间有何差异.
主要方法:
- 使用2022年国家健康和衰老趋势研究 (N=4623) 的数据进行横截面分析.
- 包括65岁及以上的社区生活的美国医疗保险受益人,进行认知,听力和视觉评估.
- 估计与至少一个客观测量的感官风险因素相关的痴呆症人口归因分数 (PAF).
主要成果:
- 至少有一个感官风险因素的患病率为66%,痴呆症影响人口的9%.
- 显著的57%的痴呆症患病率与至少一个感官风险因素相关 (95% CI: 8%-61%).
- 在年轻的老年人 (<80岁),非西班牙裔白人个人和收入较高的人群中观察到更高的PAF,性别之间发现一致.
结论:
- 在美国,多达57%的痴呆病例与临床显著的感官障碍有关.
- 针对听力和视力损失等感官缺陷的干预措施是国家痴呆风险降低战略的一个有希望的途径.
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