人类西尼罗病毒感染:对最近的全球数据 (2019-24) 的元分析
Ahmad Adebayo Irekeola1,2, Ahmad A Alshehri3,4
1Basic Sciences Unit, School of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kota Bharu, Kelantan, Malaysia.
Journal of global health
|October 17, 2025
概括
西尼罗病毒 (WNV) 血清流行率在全球为3.6%,北美和非洲的发病率更高. 加强献血者查和诊断对于缓解WNV传播至关重要.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 西尼罗河病毒 (WNV) 是一种重要的树冠病毒,分布广泛,引起公众健康的关注.
- 人类WNV感染的确切全球患病率在很大程度上是未知的.
- 这项研究旨在更新对全球近期人类WNV感染患病率的理解.
研究的目的:
- 系统地审查和元分析全球人类西尼罗河病毒感染的流行情况.
- 为不同地区和不同人群提供WNV感染的综合流行率估计.
- 为预防和控制WNV的公共卫生战略提供信息.
主要方法:
- 按照标准报告准则进行系统审查和元分析.
- 在四个电子数据库中搜索了关于WNV流行情况的相关研究.
- 雇佣德西蒙尼-莱尔德随机效应模型用于聚合流行率估计和乔安娜·布里格斯研究所的质量评估工具.
主要成果:
- 人类WNV的全球聚合血清流行率为3.6% (95%CI:2.0,6.5),北美显示最高率 (18.8%).
- 非洲报告的血清流行率为4.8% (95%CI:1.7,13.2),而南美洲的血清流行率最低 (1.7%).
- 在全球范围内,分子流行率估计为0.1%.
结论:
- 尽管全球WNV流行率相对较低,但有针对性的干预措施是必要的.
- 迫切需要在高血清流行地区加强献血者查.
- 建议整合先进的诊断和协调的报告协议,以减少跨境传播.
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