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Updated: May 8, 2026

The Generation of Closed Femoral Fractures in Mice: A Model to Study Bone Healing
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在小鼠骨骨折模型中,FGFR3功能增益延迟了膜内骨愈合

Huiting Bian1, Masahito Fujio1, Masaki Matsushita2

  • 1Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

Biochemical and biophysical research communications
|October 17, 2025
PubMed
概括

纤维细胞生长因子受体3 (FGFR3) 负面调节膜内骨愈合. 功能获取FGFR3通过抑制骨质细胞和骨质细胞活性来延迟骨折修复.

关键词:
骨髓质形成不良症 (Achondroplasia) 是一种卡尔瓦里骨折 卡尔瓦里骨折纤维细胞生长因子受体3内膜性骨愈合的方法

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相关概念视频

Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...