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Updated: Jan 14, 2026

Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology
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Longitudinal Measurement of Extracellular Matrix Rigidity in 3D Tumor Models Using Particle-tracking Microrheology

Published on: June 10, 2014

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Sp1机械传导调节了乳腺癌细胞在工程粘性弹性细胞外基质中侵入的过程

Abhishek Sharma1, Rowan F Steger2, Jen M Li3

  • 1Department of Mechanical Engineering, University of California, Santa Barbara, Santa Barbara, CA, USA.

Biomaterials
|October 17, 2025
PubMed
概括

瘤微环境的刚性和压力放松影响乳腺癌的进展. 机械反应性转录因子Sp1驱动恶性特征,与患者存活率降低相关,突出其在癌症信号传递中的作用.

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Cell-matrix's Response to Mechanical Forces

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